Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin

Following a double-blind, placebo-controlled, parallel group design, we utilized an ultra-high field multimodal brain imaging approach and demonstrated that psilocybin (0.17 mg/kg) induced region-dependent alterations in glutamate, which predicted distortions in the subjective experience of one’s self (ego dissolution).  Nature Seems reduced activity in the default mode network correlates with increased ego dissolution. Interestingly, both regular […]

The South Atlantic Anomaly

ESA reports that over the last 200 years, the magnetic field over the south Atlantic has lost around 9% of its strength. Nobody knows if this correlates with an overdue magnetic pole reversal, but I’m intrigued to be living in the epicenter.

TIL: Zettelkasten

German for ‘note box’ or ‘index cards’. Method for organizing ideas and notes. Unstructured Notes + Bidirectional Links + Taxonomy. One note = one idea (atomicity). AKA scrapbooking for librarians. Haven’t tried Roam Research but have previously used NotationalVelocity, VoodooPad and Workflowy. See also: /r/zettelkasten, project xanadu. via @artsoares

Above all, we understand we went way too far. Our reckless actions have burned the house we live in. We conceived of ourselves as separated from nature, we felt cunning and almighty. Alessandro Michele


This is delightful; A fifty-year old Philip Glass recording has resurfaced. 21 minutes of instantly recognizable minimalist notes, recently recorded by members of the Philip Glass Ensemble from home. Via Kottke.